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The Second Avenue Line is a public transit line in Manhattan, New York City, United States, running mostly along Second Avenue from Lower Manhattan to East Harlem. Originally a streetcar line, it is now the southbound direction of the M15 bus, operated by the New York City Transit Authority out of the 126th Street Bus Depot.


The Second Avenue Railroad opened the line in 1853 and 1854, from Peck Slip on the East River north along Pearl Street, the Bowery (shared with the Third Avenue Line), Grand Street, Chrystie Street, and Second Avenue to East Harlem. A short branch was later built along Stuyvesant Street and Astor Place to end at Broadway in NoHo. The Metropolitan Street Railway leased the line in January 1898, and on April 3 the line from Astor Place to Manhattan was electrified. The original line was later electrified to the Bowery, where streetcars used the Third Avenue Line to City Hall, and the line to Peck Slip was abandoned. Buses were substituted for streetcars by the East Side Omnibus Corporation on June 25, 1933. The New York City Board of Transportation took over operations in 1948, with the New York City Transit Authority replacing it in 1953.

Current bus routes in Manhattan
M1 - M2 - M3 - M4 - M5 - M6 - M7 - M8 - M9 - M10 - M11 - M14 - M15 - M16 - M18 - M20 - M21 - M22 - M23 - M27 - M30 - M31 - M34 - M35 - M42 - M50 - M57 - M60 - M66 - M72 - M79 - M86 - M96 - M98 - M100 - M101 - M102 - M103 - M104 - M106 - M116

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